Green Analytical Toxicology procedure for determination of ketamine, its metabolites and analogues in oral fluid samples using DLLME
Este estudo teve como objetivo desenvolver um método analítico para determinação de cetamina, seus metabólitos (norcetamina e 6-hidroxi-norcetamina) e seus análogos (2-fluorodesclorocetamina e desclorocetamina), utilizando DLLME e LC-MS/MS, e seguindo o conceito de toxicologia analítica verde. Link para o artigo completo: https://doi.org/10.1093/jat/bkae018
Green analytical toxicology method for determination of synthetic cathinones in oral fluid samples by microextraction by packed sorbent and liquid chromatography–tandem mass spectrometry
We developed and validated a method for quantitative analysis of ten synthetic cathinones in oral fluid (OF) samples, using microextraction by packed sorbent (MEPS) for sample preparation followed by liquid chromatography‒tandem mass spectrometry (LC‒MS/MS). OF samples were collected with a Quantisal™ device and 200 µL was extracted using a C18 MEPS cartridge installed on a […]
