Development and validation of quantitative analytical method for 50 drugs of antidepressants, benzodiazepines and opioids in oral fluid samples by liquid chromatography–tandem mass spectrometry

Abstract Purpose We developed and validated a method for quantitative analysis of 50 psychoactive substances and metabolites (antidepressants, benzodiazepines and opioids) in oral fluid samples using simple liquid–liquid extraction procedure followed by liquid chromatography–tandem mass spectrometry (LC–MS/MS). artigo completo: https://link.springer.com/article/10.1007/s11419-020-00561-8

Green analytical toxicology method for determination of synthetic cathinones in oral fluid samples by microextraction by packed sorbent and liquid chromatography–tandem mass spectrometry

We developed and validated a method for quantitative analysis of ten synthetic cathinones in oral fluid (OF) samples, using microextraction by packed sorbent (MEPS) for sample preparation followed by liquid chromatography‒tandem mass spectrometry (LC‒MS/MS). OF samples were collected with a Quantisal™ device and 200 µL was extracted using a C18 MEPS cartridge installed on a […]

Análise de fios de cabelo identifica substâncias químicas das devastadoras drogas K

A análise de fios de cabelo vai ajudar as autoridades de saúde de São Paulo a identificar substâncias químicas nas chamadas drogas K – que provocam efeitos devastadores. matéria completa: https://g1.globo.com/jornal-nacional/noticia/2023/07/20/analise-de-fios-de-cabelo-identifica-substancias-quimicas-das-devastadoras-drogas-k.ghtml?utm_source=whatsapp&utm_medium=share-bar-mobile&utm_campaign=materias